Teno-Em

Teno-Em is a generic PrEP formulation manufactured in Thailand.

2012 - According to a 2012 bioequivalence study comparing 'Teno-Em 300/200 and original medication, the conclusion was that Teno-Em 300/200mg tablets manufactured by GPO Thailand when compared with the reference product Original Medication 300/200mg tablets manufactured in Germany met the bioequivalence criteria (90% confident interval for the ratio of geometric least squares means within 80.00-125.00%) with respect to the rate and extent of absorption of tenofovir and emtricitabine. Therefore, the two formulations were bioequivalent and could be used interchangeably.

2013 - The Bangkok Tenofovir Study (Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand : a randomised, double-blind, placebo-controlled phase 3 trial) was published in The Lancet. 2014 - the Thailand National Guidelines on HIV/AIDS Treatment and Prevention 2014 has listed Teno-Em 300/200 as a medication to be used for HIV prevention (pre-exposure prophylaxis) and for the treatment of HIV infection.

2016 - 56 Dean street / IwantPrEPnow.co.uk has purchased Teno-Em from Pulse Clinic and has tested the medication by taking a blood test which detects the levels of the active drugs tenofovir (TDF) and emtricitabine (FTC) (PrEP protection) in the blood. This procedure is known as therapeutic drug monitoring (TDM) and they have had satisfactory results with Teno-Em.

2017 - The Thai AIDS Society has launched Thailand National Guidelines on HIV/AIDS Treatment and Prevention 2017 and has included Teno-Em as HIV prevention provided by all national government hospitals (Chapter 3, page 346)

Manufacturer // Distributor // Marketer : The Government Pharmaceutical Organization (GPO)

Contents : tenofovir disoproxil fumarate 300 mg, emtricitabine 200 mg

Indications / Uses : Prevention and treatment of HIV-1 infection in combination with other antiretroviral agents eg., NNRTIs or PIs.

Dosage / Direction for Use : Adult 1 tablet once daily.

Administration : May be taken with or without food; to be taken consistently either always with or always without food.

=See also=
 * Pre-exposure prophylaxis
 * Post-exposure prophylaxis
 * Post-exposure prophylaxis for HIV infection in Singapore
 * Importing/bringing antiretroviral drugs into Singapore
 * PrEP Online
 * PrEP Singapore

=References=
 * Teno-Em, Pulse Clinic's website:[]

=Acknowledgements=

This article was written by Roy Tan.